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About Us

The Case Western Reserve University School of Medicine has established the first Ph.D. and M.S. program in Systems Biology and Bioinformatics (SYBB) in the State of Ohio. Based in the School of Medicine, with the Center for Proteomics and Bioinformatics as its administrative home, the faculty cohort includes faculty from multiple departments and schools, and the fundamental core competencies for this program include: genes and proteins; bioinformatics and computational biology; and quantitative analysis and modeling with an emphasis on molecular systems biology.

The first cohort of students will begin the program in the fall of 2011. Students will be admitted through direct admission, or the School of Medicine's Biomedical Research Training Program (BSTP) or the Medical Science Training Program (MSTP).

The Systems Biology and Bioinformatics Ph.D. program at CWRU offers trainees the opportunity to combine both experimental and computational or mathematical disciplines to understand complex biological systems. The goal of this program is to produce scientists who are familiar with multiple disciplines and equipped to conduct interdisciplinary research.

The SYBB program will train scientists who are able to generate and analyze experimental data for biomedical research and to develop physical or computational models of the molecular components that drive the behavior of a biological system.

The SYBB program includes faculty and coursework from multiple departments and across the CWRU campus. Participating departments and centers include:

  • Biology
  • Biomedical Engineering
  • Center for Proteomics and Bioinformatics
  • Electrical Engineering and Computer Science
  • Epidemiology and Biostatistics
  • Genetics
  • Mathematics
  • Physiology and Biophysics
  • Pharmacology

Program Competencies

The specific academic requirements of the SYBB Program are intended to provide students with a required core curriculum in Systems Biology and a set of electives designed both to assure minimum competencies in three Fundamental Core Competencies and equip them for their particular thesis research discipline. Each trainee will be guided in a course of study by a mentoring committee to ensure the completion of training in the program competencies as well as maintenance of a focus on molecular systems theory.

Fundamental Core Competencies

  • Genes and proteins
  • Bioinformatics and Computational Biology
  • Quantitative Analysis and Modeling